Search results for "vidējās cerebrālās artērijas oklūzijas modelis"

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Peļu smadzeņu garozas mitohondriālās elpošanas novērtējums pēc vidējās cerebrālās artērijas oklūzijas

2020

Insults ir otrais vadošais nāves cēlonis un galvenais invaliditātes cēlonis pasaulē. Pētījumi parāda, ka smadzeņu mitohondriju funkciju traucējumiem ir svarīga nozīme cerebrālā infarkta patoģenēzē. Darba mērķis bija izpētīt cerebrālā infarkta ietekmi uz mitohondriālo elpošanu peļu smadzeņu garozas audos. Pētījuma rezultāti parādīja, ka vienu stundu pēc vidējās cerebrālās artērijas oklūzijas statistiski ticami intensīvāka mitohondriālā elpošana saistīta ar I un II kompleksu noris insulta grupas peļu smadzeņu kontralaterālās (insulta neskartās) puslodes garozas paraugos salīdzinot ar kontroles grupas kontralaterālās puses paraugiem. Iegūtie dati var liecināt par adaptīviem procesiem un metabo…

peļu smadzeņu garozas audividējās cerebrālās artērijas oklūzijas modelismitohondriālā skābekļa mērījumiMedicīnacerebrāls infarkts

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PEPhysical Sciences and Engineering
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LSLife Sciences
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